Nitroxyl (HNO) as a vasoprotective signaling molecule.

@article{Bullen2011NitroxylA,
  title={Nitroxyl (HNO) as a vasoprotective signaling molecule.},
  author={Michelle L. Bullen and Alyson Anne Miller and Karen L. Andrews and Jennifer C. Irvine and Rebecca Helen Ritchie and Christopher G. Sobey and Barbara K Kemp-Harper},
  journal={Antioxidants \& redox signaling},
  year={2011},
  volume={14 9},
  pages={
          1675-86
        }
}
Nitroxyl (HNO), the one electron reduced and protonated form of nitric oxide (NO(•)), is rapidly emerging as a novel nitrogen oxide with distinct pharmacology and therapeutic advantages over its redox sibling. Whilst the cardioprotective effects of HNO in heart failure have been established, it is apparent that HNO may also confer a number of vasoprotective properties. Like NO(•), HNO induces vasodilatation, inhibits platelet aggregation, and limits vascular smooth muscle cell proliferation. In… 

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