Nitrous oxide: still useful in the year 2000?

  title={Nitrous oxide: still useful in the year 2000?},
  author={Michael F M James},
  journal={Current opinion in anaesthesiology},
  volume={12 4},
The risk-benefit ratio of using nitrous oxide has been debated for many years. In this article the adverse effects of nitrous oxide on patient well-being, including its role in postoperative nausea and vomiting, its toxic effects and adverse physiological changes are reviewed. Guidelines for the rational use of the drug are suggested.