Nitrous Oxide and Xenon Prevent Amphetamine-Induced Carrier-Mediated Dopamine Release in a Memantine-Like Fashion and Protect Against Behavioral Sensitization

@article{David2006NitrousOA,
  title={Nitrous Oxide and Xenon Prevent Amphetamine-Induced Carrier-Mediated Dopamine Release in a Memantine-Like Fashion and Protect Against Behavioral Sensitization},
  author={H. N. David and M. Ansseau and M. Lemaire and J. Abraini},
  journal={Biological Psychiatry},
  year={2006},
  volume={60},
  pages={49-57}
}
BACKGROUND Amphetamine administration induces stimulation-independent dopamine release in the nucleus accumbens (NAcc) through reverse dopamine transport, a critical neurochemical event involved in its psychostimulant action, and furthermore decreases stimulation-dependent vesicular dopamine release. These effects may involve possible indirect glutamatergic mechanisms. METHODS We investigated the effects of nitrous oxide and xenon, which possess antagonistic action at the N-methyl-D-aspartate… Expand
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