Nitroso–Redox Interactions in the Cardiovascular System

  title={Nitroso–Redox Interactions in the Cardiovascular System},
  author={Jeffrey M. Zimmet and Joshua M. Hare},
ormal cardiovascular performance requires exquisitebalancing of many complex biochemical processes.Perturbation of this balance may lead to myocardial dysfunc-tion or may be a secondary result of structural heart diseasesuch as myocardial infarction (MI) or cardiomyopathic pro-cesses. Altered signaling systems in turn contribute to theprogression of myocardial dysfunction. The roles of reactiveoxygen species (ROS) and reactive nitrogen species (RNS) innormal and failing myocardium and… 

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