Nitrosamine metabolism in protein-deficient weanling rats during the process of repletion.

@article{Maduagwu1989NitrosamineMI,
  title={Nitrosamine metabolism in protein-deficient weanling rats during the process of repletion.},
  author={Emmanuel Ndubuisi Maduagwu},
  journal={Annals of nutrition & metabolism},
  year={1989},
  volume={33 1},
  pages={49-56}
}
The metabolism of N-nitrosodimethylamine (NDMA) during a 5- to 10-day process of 20% protein repletion was investigated, in vitro and in vivo, in male weanling albino Wistar rats acutely and chronically deprived of protein by feeding, respectively, diets containing no protein or 3.5% for 7 days and one with 3.5% protein for 35 days. Results of experiments using the 5-day rehabilitated animals showed that rate of NDMA demethylation by liver microsomal preparation was 3-fold higher in the… CONTINUE READING