Nitrophenols isolated from diesel exhaust particles promote the growth of MCF-7 breast adenocarcinoma cells.

@article{Furuta2008NitrophenolsIF,
  title={Nitrophenols isolated from diesel exhaust particles promote the growth of MCF-7 breast adenocarcinoma cells.},
  author={C. Furuta and A. Suzuki and G. Watanabe and Chunmei Li and S. Taneda and K. Taya},
  journal={Toxicology and applied pharmacology},
  year={2008},
  volume={230 3},
  pages={
          320-6
        }
}
Diesel exhaust particles (DEPs) cause many adverse health problems, and reports indicate increased risk of breast cancer in men and women through exposure to gasoline and vehicle exhaust. However, DEPs include vast numbers of compounds, and the specific compound(s) responsible for these actions are not clear. We recently isolated two nitrophenols from DEPs-3-methyl-4-nitrophenol (4-nitro-m-cresol; PNMC) and 4-nitro-3-phenylphenol (PNMPP)-and showed that they had estrogenic and anti-androgenic… Expand
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