Nitrone Derivatives as Therapeutics: From Chemical Modification to Specific-targeting.

Abstract

Nitrones have been extensively used for the detection of transient free radicals using electron paramagnetic resonance. Since the mid-80's, nitrones have also been widely used as protective agents against oxidative stress in several biological models. Due to the high potency of nitrones, there has been extensive research on the development of derivatives… (More)
DOI: 10.2174/1568026617666170303115324

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