Nitrogenase MoFe-protein at 1.16 A resolution: a central ligand in the FeMo-cofactor.

@article{Einsle2002NitrogenaseMA,
  title={Nitrogenase MoFe-protein at 1.16 A resolution: a central ligand in the FeMo-cofactor.},
  author={Oliver Einsle and F Akif Tezcan and Susana L A Andrade and Benedikt Schmid and Mika Yoshida and James W. Howard and Douglas C Rees},
  journal={Science},
  year={2002},
  volume={297 5587},
  pages={1696-700}
}
A high-resolution crystallographic analysis of the nitrogenase MoFe-protein reveals a previously unrecognized ligand coordinated to six iron atoms in the center of the catalytically essential FeMo-cofactor. The electron density for this ligand is masked in structures with resolutions lower than 1.55 angstroms, owing to Fourier series termination ripples from the surrounding iron and sulfur atoms in the cofactor. The central atom completes an approximate tetrahedral coordination for the six iron… CONTINUE READING
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