Nitrogen starvation of cyanobacteria results in the production of β-N-methylamino-L-alanine.

  title={Nitrogen starvation of cyanobacteria results in the production of β-N-methylamino-L-alanine.},
  author={Simon{\'e} Downing and Sandra Anne Banack and J S Metcalf and Paul Cox and Timothy Grant Downing},
  journal={Toxicon : official journal of the International Society on Toxinology},
  volume={58 2},
β-N-Methylamino-L-alanine, an unusual amino acid implicated in neurodegenerative disease, has been detected in cultures of nearly all genera of environmentally ubiquitous cyanobacteria tested. The compound is present within cyanobacterial cells in free and protein-associated forms, with large variations occurring in the concentration of these pools between species as well as within single strains. With a lack of knowledge and supporting data on the regulation of BMAA production and the role of… CONTINUE READING
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