Nitrofurantoin excretion in human milk.

  title={Nitrofurantoin excretion in human milk.},
  author={G{\'e}rard Pons and Elisabeth Rey and M. O. Richard and F Vauzelle and C. Francoual and Claude Moran and Philippe D'Athis and Jean Badoual and Georges Olive},
  journal={Developmental pharmacology and therapeutics},
  volume={14 3},
Six lactating white healthy women (26-36 years old, weighing 45-58 kg) were treated with 50 mg nitrofurantoin tablets, a urinary antiseptic. They received either 50 mg (group I; n = 3) or 100 mg (group II; n = 3) 3 times a day (09.00, 16.00, 19.00 h) for 24 h, 2-5 days after the delivery of a full-term neonate. The study was performed on the 4th dose at 09.00 h just before breakfast. Milk samples were collected before, 3 and 6 h after the nitrofurantoin administration with an Egnell SMB breast… CONTINUE READING