Nitroarachidonic acid prevents NADPH oxidase assembly and superoxide radical production in activated macrophages.

Abstract

Nitration of arachidonic acid (AA) to nitroarachidonic acid (AANO2) leads to anti-inflammatory intracellular activities during macrophage activation. However, less is known about the capacity of AANO2 to regulate the production of reactive oxygen species under proinflammatory conditions. One of the immediate responses upon macrophage activation involves the… (More)
DOI: 10.1016/j.freeradbiomed.2012.12.020

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