Nitrile-Promoted Alkene Epoxidation with Urea–Hydrogen Peroxide (UHP)

@article{Ji2013NitrilePromotedAE,
  title={Nitrile-Promoted Alkene Epoxidation with Urea–Hydrogen Peroxide (UHP)},
  author={Li Ji and Yana Wang and Chao Qian and Xinzhi Chen},
  journal={Synthetic Communications},
  year={2013},
  volume={43},
  pages={2256 - 2264}
}
Abstract An efficient method for alkene epoxidation has been studied systematically using benzonitrile and the complex urea–hydrogen peroxide (UHP), which is an anhydrous form of hydrogen peroxide and has the potential to release hydrogen peroxide in a controlled manner and thus avoid the need to slowly add aqueous H2O2 to the reaction mixture. The absence of water in the reaction media was also beneficial, because it minimized undesired reactions of the oxidized products. A range of alkenes… 
15 Citations
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