Nitric oxide synthase inhibition selectively potentiates swim stress antinociception in rats.

@article{Spinella1994NitricOS,
  title={Nitric oxide synthase inhibition selectively potentiates swim stress antinociception in rats.},
  author={Marcello Spinella and Richard J Bodnar},
  journal={Pharmacology, biochemistry, and behavior},
  year={1994},
  volume={47 3},
  pages={727-33}
}
Since nitric oxide (NO) has been implicated in nociceptive processing, the present study examined whether NO synthase inhibition with either Nw-nitro-L-arginine (L-NA) or its methyl ester (L-NAME) would alter antinociception elicited by either continuous (CCWS) or intermittent cold-water swims (ICWS) on the tail-flick and jump tests. Whereas CCWS… CONTINUE READING