Nitric oxide synthase inhibition impairs myocardial efficiency and ventriculo-arterial matching in acute ischemic heart failure.

Abstract

BACKGROUND AND AIMS The effect of nitric oxide (NO) manipulation in acute heart failure has not been sufficiently investigated. Therefore, we assessed the impact of NO-synthase (NOS) inhibition on left ventricular (LV) function and energetics as well as overall hemodynamics, in a porcine model of acute ischemic LV failure. METHODS Acute heart failure was… (More)

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@article{Nordhaug2004NitricOS, title={Nitric oxide synthase inhibition impairs myocardial efficiency and ventriculo-arterial matching in acute ischemic heart failure.}, author={Dag Ole Nordhaug and Tor Steensrud and Ebrahim Aghajani and Christian Korvald and Truls Myrmel}, journal={European journal of heart failure}, year={2004}, volume={6 6}, pages={705-13} }