Nitric oxide synthase in the visual cortex of monocular monkeys as revealed by light and electron microscopic immunocytochemistry.

@article{Aoki1993NitricOS,
  title={Nitric oxide synthase in the visual cortex of monocular monkeys as revealed by light and electron microscopic immunocytochemistry.},
  author={Chiye J Aoki and S. B. Fenstemaker and Martin Lubin and Cheer Germ Go},
  journal={Brain research},
  year={1993},
  volume={620 1},
  pages={97-113}
}
Recent results indicate that nitric oxide (NO) can play an important role in neuronal excitability by modifying the strength of activated synapses and regulating local cerebral blood flow. We sought to determine whether the level of NO synthase (NOS) could, in turn, also be regulated by neural activity. Results using a polyclonal anti-NOS antibody showed that, in cortical area V1 of monocular monkeys, NOS-immunoreactivity is diminished in lamina 4C neuropil of the deprived ocular dominance… CONTINUE READING