Nitric oxide synthase in atherosclerosis and vascular injury: insights from experimental gene therapy.

@article{Channon2000NitricOS,
  title={Nitric oxide synthase in atherosclerosis and vascular injury: insights from experimental gene therapy.},
  author={Keith M. Channon and Hai-yan Qian and Suja Elizabeth George},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={2000},
  volume={20 8},
  pages={1873-81}
}
Gene therapy aims to intervene in a disease process by transfer and expression of specific genes in a target tissue or organ. Cardiovascular gene therapy in humans remains in its infancy, but in the last decade, experimental gene transfer has emerged as a powerful biological tool to investigate the function of specific genes in vascular disease pathobiology. Nitric oxide synthases, the enzymes that produce nitric oxide, have received considerable attention as potential candidates for vascular… CONTINUE READING

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