Nitric oxide release from normal and dysfunctional endothelium.

  title={Nitric oxide release from normal and dysfunctional endothelium.},
  author={Victor Brovkovych and Lawrence W. Dobrucki and Svitlana D Brovkovych and Iwona T. Dobrucki and Carlos Antonio do Nascimento and Andrzej Burewicz and Tadeusz Malinski},
  journal={Journal of physiology and pharmacology : an official journal of the Polish Physiological Society},
  volume={50 4},
The endothelium plays a critical role in maintaining vascular tone by releasing vasoconstrictor and vasodilator substances. Endothelium - derived nitric oxide (NO) is a vasodilator rapidly inactivated by superoxide (O2-) found in significant quantities. The porphyrinic sensor (0.5-8 microm diameter) and chemiluminescence methods were used to measure NO and… CONTINUE READING