Nitric oxide regulates vascular calcification by interfering with TGF- signalling.

@article{Kanno2008NitricOR,
  title={Nitric oxide regulates vascular calcification by interfering with TGF- signalling.},
  author={Yosuke Kanno and Takeshi Into and Charles J Lowenstein and Kenji Matsushita},
  journal={Cardiovascular research},
  year={2008},
  volume={77 1},
  pages={221-30}
}
AIMS Vascular calcification often occurs with advancing age, atherosclerosis, and metabolic disorders such as diabetes mellitus and end-stage renal disease. Vascular calcification is associated with cardiovascular events and increased mortality. Nitric oxide (NO) is crucial for maintaining vascular function, but little is known about how NO affects vascular calcification. The aim of this study was to examine the effect of NO on vascular calcification. METHODS AND RESULTS In this study, we… CONTINUE READING
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