Nitric oxide regulates axonal regeneration in an insect embryonic CNS.

@article{Stern2008NitricOR,
  title={Nitric oxide regulates axonal regeneration in an insect embryonic CNS.},
  author={Michael Stern and Gerd Bicker},
  journal={Developmental neurobiology},
  year={2008},
  volume={68 3},
  pages={295-308}
}
In higher vertebrates, the central nervous system (CNS) is unable to regenerate after injury, at least partially because of growth-inhibiting factors. Invertebrates lack many of these negative regulators, allowing us to study the positive factors in isolation. One possible molecular player in neuronal regeneration is the nitric oxide (NO)-cyclic guanosine-monophosphate (cGMP) transduction pathway which is known to regulate axonal growth and neural migration. Here, we present an experimental… CONTINUE READING