Nitric oxide plasma concentration associated with cognitive impairment in patients with recurrent depressive disorder.

@article{Talarowska2012NitricOP,
  title={Nitric oxide plasma concentration associated with cognitive impairment in patients with recurrent depressive disorder.},
  author={Monika Talarowska and Piotr Gałecki and Michael Maes and Agata Orzechowska and Marcelina Chamielec and Grzegorz Bartosz and Edward Kowalczyk},
  journal={Neuroscience letters},
  year={2012},
  volume={510 2},
  pages={127-31}
}
BACKGROUND/AIM Depressive disorders are multifactorial diseases, in which cognitive impairment is one of the characteristic feature. One of the molecules that regulate of various cognitive, emotional and behavioural processes is nitric oxide (NO), synthesized from l-arginine by a family of isoformic enzymes known as nitric oxide synthases (NOS). NO is a gaseous compounds that acts as a biological second messenger in a number of organ system. In addition, NO is a ubiquitous free radical (NO… CONTINUE READING