Nitric oxide mediates the increase in local cerebral blood flow during focal seizures.

@article{Vasconcelos1995NitricOM,
  title={Nitric oxide mediates the increase in local cerebral blood flow during focal seizures.},
  author={A Pereira de Vasconcelos and Roger A. Baldwin and Claude Guy Wasterlain},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1995},
  volume={92 8},
  pages={3175-9}
}
The role of nitric oxide (NO) in the increase in local cerebral blood flow (LCBF) elicited by focal cortical epileptic seizures was investigated in anesthetized adult rats. Seizures were induced by topical bicuculline methiodide applied through two cranial windows drilled over homotopic sites of the frontal cortex, and LCBF was measured by quantitative… CONTINUE READING