Nitric oxide mediates sexual behavior in female rats.

@article{Mani1994NitricOM,
  title={Nitric oxide mediates sexual behavior in female rats.},
  author={Shaila K Mani and Julia Allen and Val{\'e}ria Rettori and S M Mccann and Bert W O'malley and James H. Clark},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1994},
  volume={91 14},
  pages={6468-72}
}
Nitric oxide (NO), an active free radical formed during the conversion of arginine to citrulline by the enzyme NO synthase (NOS), mediates vasorelaxation, cytotoxicity, and neurotransmission. Neurons containing NOS (NOergic) are located in the hypothalamus. These NOergic neurons control the release of several hypothalamic peptides. Release of NO from these NOergic neurons stimulates pulsatile release of luteinizing hormone-releasing hormone (LHRH) in vivo and LHRH release in vitro. LHRH not… CONTINUE READING

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