Nitric oxide mediates lung vascular permeability and lymph-borne IL-6 after an intestinal ischemic insult.

@article{BreithauptFaloppa2009NitricOM,
  title={Nitric oxide mediates lung vascular permeability and lymph-borne IL-6 after an intestinal ischemic insult.},
  author={Ana Cristina Breithaupt-Faloppa and Luana Beatriz Vitoretti and Fernando Rodrigues Coelho and Adriana Lino dos Santos Franco and Helori Vanni Domingos and Lia Siguemi Sudo-Hayashi and Ricardo Martins de Oliveira-Filho and Wothan Tavares de Lima},
  journal={Shock},
  year={2009},
  volume={32 1},
  pages={55-61}
}
Acute lung injury following intestinal I/R depends on neutrophil-endothelial cell interactions and on cytokines drained from the gut through the lymph. Among the mediators generated during I/R, increased serum levels of IL-6 and NO are also found and might be involved in acute lung injury. Once intestinal ischemia itself may be a factor of tissue injury, in… CONTINUE READING