Nitric oxide-mediated modulation of the murine locomotor network

@inproceedings{Foster2014NitricOM,
  title={Nitric oxide-mediated modulation of the murine locomotor network},
  author={Joshua D Foster and Catherine Dunford and Keith Thomas Sillar and Gareth Miles},
  booktitle={Journal of neurophysiology},
  year={2014}
}
Spinal motor control networks are regulated by neuromodulatory systems to allow adaptability of movements. The present study aimed to elucidate the role of nitric oxide (NO) in the modulation of mammalian spinal locomotor networks. This was investigated with isolated spinal cord preparations from neonatal mice in which rhythmic locomotor-related activity was induced pharmacologically. Bath application of the NO donor diethylamine NONOate (DEA/NO) decreased the frequency and modulated the… CONTINUE READING

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