Nitric oxide may prevent hypertension early in diabetes by counteracting renal actions of superoxide.

Abstract

The dependence of blood pressure on a balance between superoxide and nitric oxide may be amplified in diabetes. We have shown that the first occurrence of sustained hyperglycemia in type I diabetes causes hypertension when induced in rats that have had nitric oxide synthesis blocked chronically (L-NAME, 10 microg/kg per minute IV). This study used tempol… (More)

7 Figures and Tables

Topics

Statistics

0102030'05'06'07'08'09'10'11'12'13'14'15'16'17'18
Citations per Year

96 Citations

Semantic Scholar estimates that this publication has 96 citations based on the available data.

See our FAQ for additional information.

  • Presentations referencing similar topics