Nitric oxide-like activity in guinea pig colon as determined by effector responses, bioassay and chemiluminescence analysis.

@article{Iversen1994NitricOA,
  title={Nitric oxide-like activity in guinea pig colon as determined by effector responses, bioassay and chemiluminescence analysis.},
  author={Hanne Iversen and Nils Peter Wiklund and Lars. E. Gustafsson},
  journal={Acta physiologica Scandinavica},
  year={1994},
  volume={152 3},
  pages={
          315-22
        }
}
The role of nerve-induced release of nitric oxide (NO) as a modulator of neuroeffector transmission was studied in the longitudinal muscle of the guinea pig colon. The biological activity of a vascular relaxing factor released by nerve stimulation was examined in a bioassay cascade system. Furthermore, biochemical measurements of nerve-induced release of the NO metabolite nitrite (NO2-) were made with a chemiluminescence technique. Transmural nerve stimulation elicited contractile responses… CONTINUE READING
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