Nitric oxide in human fetal membranes at term gestation: effect on prostaglandin E2 release.

@article{Ticconi1996NitricOI,
  title={Nitric oxide in human fetal membranes at term gestation: effect on prostaglandin E2 release.},
  author={Carlo Ticconi and Alessandra Zicari and Anna Losardo and Giuseppe Mario Pontieri and Nino Pasetto and Emilio Piccione},
  journal={European journal of obstetrics, gynecology, and reproductive biology},
  year={1996},
  volume={69 2},
  pages={
          135-9
        }
}
OBJECTIVES To examine the in vitro release of nitric oxide (NO) by human fetal membranes at term gestation and to investigate whether NO could stimulate prostaglandin E2 (PGE2) release by these tissues. STUDY DESIGN Explants of fetal membranes (n = 17) were incubated either in the presence of sodium nitroprusside (NP), or L-Arginine (L-Arg), or bacterial lipopolysaccharide (LPS), or in the absence of the above substances (controls). NO and PGE2 concentrations in culture medium were assayed by… CONTINUE READING