Nitric oxide gas infusion to the oxygenator enhances the biocompatibility of heparin coated extracorporeal bypass circuits.

@article{Hayashi1998NitricOG,
  title={Nitric oxide gas infusion to the oxygenator enhances the biocompatibility of heparin coated extracorporeal bypass circuits.},
  author={Yoshihiro Hayashi and Yoshiki Sawa and Motonobu Nishimura and Jae Hyuk Chang and Akira Amemiya and Koji Kagisaki and Satoshi Taketani and Takahiro Yamaguchi and Naoto Hirata and Shigeaki Ohtake and Hikaru Matsuda},
  journal={ASAIO journal},
  year={1998},
  volume={44 5},
  pages={M456-61}
}
Heparin coated bypass circuits have been reported to improve the biocompatibility of extracorporeal circulation, although it is still insufficient and improvable. Nitric oxide (NO) is known to inhibit platelet activation and inflammatory reactions. In this study, the authors evaluated exogenous NO infusion in enhancing the effect of a heparin coated bypass… CONTINUE READING