Nitric oxide evoked p53-accumulation and apoptosis.


The tumor suppressor p53 accumulates under conditions of cellular stress and affects cell cycle progression and/or apoptosis. This has been exemplified for endogenously produced or exogenously supplied nitric oxide (NO) and thus accounts at least in part for cell destructive signaling qualities of this bioactive molecule and/or derived reactive nitrogen… (More)


Cite this paper

@article{Brne2003NitricOE, title={Nitric oxide evoked p53-accumulation and apoptosis.}, author={Bernhard Br{\"u}ne and Nicole Schneiderhan}, journal={Toxicology letters}, year={2003}, volume={139 2-3}, pages={119-23} }