Nitric oxide drives embryonic myogenesis in chicken through the upregulation of myogenic differentiation factors.

@article{Cazzato2014NitricOD,
  title={Nitric oxide drives embryonic myogenesis in chicken through the upregulation of myogenic differentiation factors.},
  author={Denise Cazzato and Emma Assi and Claudia Moscheni and Silvia Brunelli and Clara De Palma and Davide Cervia and Cristiana Perrotta and Emilio Clementi},
  journal={Experimental cell research},
  year={2014},
  volume={320 2},
  pages={269-80}
}
The muscle-specific variant of neuronal nitric oxide (NO) synthase (NOS-I), is developmentally regulated in mouse suggesting a role of NO during myogenesis. In chick embryo, a good model of development, we found that the expression of NOS-I is up-regulated, but only in the early phase of development. Through a pharmacological intervention in ovo we found that NO signalling plays a relevant role during embryonic development. The inhibition of NOS-I decreased the growth of embryo, in particular… CONTINUE READING

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