Nitric oxide does not mediate autoregulation of retinal blood flow in newborn pig.

@article{Gidday1995NitricOD,
  title={Nitric oxide does not mediate autoregulation of retinal blood flow in newborn pig.},
  author={Jeffrey M. Gidday and Yun Zhu},
  journal={The American journal of physiology},
  year={1995},
  volume={269 3 Pt 2},
  pages={H1065-72}
}
Isoflurane-anesthetized newborn pigs were used to test the hypothesis that nitric oxide mediates autoregulatory dilations of retinal arterioles. Fundus images were monitored by videomicroscopy at x310, and stimulus-induced changes in retinal arteriolar diameter were measured by on-line image analysis. Dilatative responses to systemic hypoxia (arterial O2 tension 20-30 mmHg), hypotension (mean arterial blood pressure 40 mmHg), or hypercapnia (arterial CO2 tension 70-85 mmHg) were assessed after… CONTINUE READING