Nitric oxide delivery system for biological media.

@article{Skinn2011NitricOD,
  title={Nitric oxide delivery system for biological media.},
  author={Brian T Skinn and Chang Hoon Lim and William M. Deen},
  journal={Free radical biology & medicine},
  year={2011},
  volume={50 2},
  pages={381-8}
}
Developing an understanding of how chronically elevated levels of nitric oxide at sites of inflammation or infection can lead to cancer and other diseases requires ways to expose cells and biomolecules to controlled concentrations of NO for hours to days. To achieve this, a small (65ml) stirred reactor was fabricated that included a flat, porous poly(tetrafluoroethylene) membrane and a loop of poly(dimethylsiloxane) tubing for NO and O(2) delivery, respectively. It was equipped with probes for… CONTINUE READING