Nitric oxide decreases ammonium release in tadpoles of the clawed frog, Xenopus laevis, Daudin

@article{Wildling2006NitricOD,
  title={Nitric oxide decreases ammonium release in tadpoles of the clawed frog, Xenopus laevis, Daudin},
  author={Stefan Wildling and Hubert H. Kerschbaum},
  journal={Journal of Comparative Physiology B},
  year={2006},
  volume={177},
  pages={401-411}
}
In the present study, we quantified the physiological consequences of nitric oxide (NO) on ammonium release in tadpoles of Xenopus laevis. Tadpoles exposed to S-nitro-N-acetylpenicillamine (SNAP), an NO-donor, or l-arginine, the substrate of NO synthase (NOS), showed a reversible decrease, whereas animals exposed to the NOS inhibitor Nω-methyl-l-arginine (l-NMMA) exhibited an increase in ammonium release. Release of ammonium may be of physiological relevance during stress response of the animal… CONTINUE READING