Nitric oxide contributes to right coronary vasodilation during systemic hypoxia.

@article{Martnez2005NitricOC,
  title={Nitric oxide contributes to right coronary vasodilation during systemic hypoxia.},
  author={Rodolfo Rub{\'e}n Trevi{\~n}o Mart{\'i}nez and Srinath Setty and Pu Zong and Johnathan D. Tune and H. Fred Downey},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2005},
  volume={288 3},
  pages={
          H1139-46
        }
}
As arterial partial pressure of O(2) (Pa(O(2))) is reduced during systemic hypoxia, right ventricular (RV) work and myocardial O(2) consumption (MVo(2)) increase. Mechanisms responsible for maintaining RV O(2) demand/supply balance during hypoxia have not been delineated. To address this problem, right coronary (RC) blood flow and RV O(2) extraction were measured in nine conscious, instrumented dogs exposed to normobaric hypoxia. Catheters were implanted in the right ventricle for measuring… CONTINUE READING

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