Nitric oxide attenuates interleukin 2‐induced lung injury

@article{BouchierHayes1997NitricOA,
  title={Nitric oxide attenuates interleukin 2‐induced lung injury},
  author={D. Bouchier-Hayes and H. Abdih and C. Kelly and M. Barry and H. Redmond and P. Burke and A. Tanner},
  journal={British Journal of Surgery},
  year={1997},
  volume={84}
}
  • D. Bouchier-Hayes, H. Abdih, +5 authors D. Bouchier-Hayes
  • Published 1997
  • Medicine
  • British Journal of Surgery
  • Background The pathogenesis of interleukin (IL) 2‐induced vascular leak syndrome may be related to neutrophil‐mediated endothelial injury. Nitric oxide inhibits neutrophil superoxide anion synthesis and adherence to endothelial cells. The role of systemic nitric oxide in preventing IL‐2‐induced lung injury was studied in an experimental model. 
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