Nitric oxide as inflammatory mediator in post-traumatic stress disorder (PTSD): evidence from an animal model

@article{Oosthuizen2005NitricOA,
  title={Nitric oxide as inflammatory mediator in post-traumatic stress disorder (PTSD): evidence from an animal model},
  author={Frasia Oosthuizen and Gregers Wegener and Brian Herbert Harvey},
  journal={Neuropsychiatric Disease and Treatment},
  year={2005},
  volume={1},
  pages={109 - 123}
}
Post-traumatic stress disorder (PTSD) is a severe anxiety disorder that may develop after experiencing or witnessing a traumatic event. Recent clinical evidence has suggested the involvement of neurodegenerative pathology in the illness, particularly with brain imaging studies revealing a marked reduction in hippocampal volume. Of greater significance is that these anatomical changes appear to be positively correlated with the degree of cognitive deficit noted in these patients. Stress-induced… CONTINUE READING

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