Nitric oxide as S-nitrosoproteins in rheumatoid arthritis.

  title={Nitric oxide as S-nitrosoproteins in rheumatoid arthritis.},
  author={Pascal Hilliquin and Didier Borderie and Alain Hernvann and Charles Jo{\"e}l Menkes and Ohvanesse Garabed Ekindjian},
  journal={Arthritis and rheumatism},
  volume={40 8},
OBJECTIVE Nitric oxide (NO) is a free radical involved in inflammation and immune reactions. The presence of NO is usually assessed by assaying its degradation products, nitrite and nitrate. NO binds to thiol-containing proteins to form S-nitrosoproteins (S-NP). The aim of this study was to investigate the presence of S-NP, together with nitrite and nitrate, in patients with rheumatoid arthritis (RA). METHODS Forty patients with RA were studied and compared with 24 patients with… CONTINUE READING


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