Nitric oxide and vascular insulin resistance

  title={Nitric oxide and vascular insulin resistance},
  author={G. Wu and C. Meininger},
  • G. Wu, C. Meininger
  • Published 2009
  • Biology, Medicine
  • BioFactors
  • Obesity and type‐II diabetes are growing major health issues worldwide. They are the leading risk factors for vascular insulin resistance, which plays an important role in the pathogenesis of cardiovascular disease, the leading cause of death in developed nations. Recent studies have shown that reduced synthesis of nitric oxide (NO; a major vasodilator) from L‐arginine in endothelial cells is a major factor contributing to the impaired action of insulin in the vasculature of obese and diabetic… CONTINUE READING
    117 Citations

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