Nitric oxide and thiol groups.

  title={Nitric oxide and thiol groups.},
  author={Benjamin M. Gaston},
  journal={Biochimica et biophysica acta},
  volume={1411 2-3},
S-Nitroso(sy)lation reactions have recently been appreciated to regulate protein function and mediate 'nitrosative' stress. S-Nitrosothiols (SNOs) have been identified in a variety of tissues, and represent a novel class of signaling molecules which may act independently of homolytic cleavage to NO - and, indeed, in a stereoselective fashion - or be metabolized to other bioactive nitrogen oxides. It is now appreciated that sulfur-NO interactions have critical physiological relevance to… CONTINUE READING

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