Nitric oxide and redox regulation in the liver: part II. Redox biology in pathologic hepatocytes and implications for intervention.

@article{Diesen2011NitricOA,
  title={Nitric oxide and redox regulation in the liver: part II. Redox biology in pathologic hepatocytes and implications for intervention.},
  author={Diana Diesen and P. C. Kuo},
  journal={The Journal of surgical research},
  year={2011},
  volume={167 1},
  pages={
          96-112
        }
}
  • Diana Diesen, P. C. Kuo
  • Published in
    The Journal of surgical…
    2011
  • Biology, Medicine
  • Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are created in normal hepatocytes and are critical for normal physiologic processes, including oxidative respiration, growth, regeneration, apoptosis, and microsomal defense. When the levels of oxidation products exceed the capacity of normal antioxidant systems, oxidative stress occurs. This type of stress, in the form of ROS and RNS, can be damaging to all liver cells, including hepatocytes, Kupffer cells, stellate cells, and… CONTINUE READING

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