Nitric oxide and preglomerular vascular lesions in lyon spontaneously hypertensive rats.

@article{Casellas2000NitricOA,
  title={Nitric oxide and preglomerular vascular lesions in lyon spontaneously hypertensive rats.},
  author={D. Casellas and N. Bouriquet and A. Artuso},
  journal={Acta physiologica Scandinavica},
  year={2000},
  volume={168 1},
  pages={
          133-8
        }
}
Accumulation of Sudan black-stainable (SB+) lipids is a hallmark of the focal inflammato-proliferative lesions that develop along preglomerular vessels in N G-nitro-L-arginine methyl ester (L-NAME) and angiotensin II hypertensive rats. We extended our findings to genetically hypertensive Lyon (LH) rats aged 14 and 30 weeks and to age-matched normotensive (LN) rats. Vessels were isolated by HCl maceration. Despite high systolic blood pressure (SBP), hypercholesterolaemia, albuminuria and… Expand

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