Nitric oxide and nitrotyrosine in the lungs of patients with acute respiratory distress syndrome.

@article{Sittipunt2001NitricOA,
  title={Nitric oxide and nitrotyrosine in the lungs of patients with acute respiratory distress syndrome.},
  author={Chanchai Sittipunt and Kenneth P. Steinberg and John T. Ruzinski and Carpantato T Myles and Shigao Zhu and Richard B. Goodman and Leonard D. Hudson and Sadis Matalon and Thomas R. Martin},
  journal={American journal of respiratory and critical care medicine},
  year={2001},
  volume={163 2},
  pages={503-10}
}
Nitric oxide (NO) end-products (nitrate and nitrite) are present in bronchoalveolar lavage (BAL) fluid of patients with inflammatory lung diseases. Reactive oxygen-nitrogen intermediates damage macromolecules by oxidation or nitration of critical residues in proteins. The goal of this study was to measure NO end-products (nitrate+ nitrite), in BAL fluid before and after the onset of acute respiratory distress syndrome (ARDS) and to determine if these products are associated with expression of… CONTINUE READING
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