Nitric oxide and apoptosis induced in Peyer's patches by attenuated strains of Salmonella enterica serovar Enteritidis.

@article{Cerquetti2002NitricOA,
  title={Nitric oxide and apoptosis induced in Peyer's patches by attenuated strains of Salmonella enterica serovar Enteritidis.},
  author={Mar{\'i}a Cristina Cerquetti and Nora Beatriz Goren and Alejandro J Ropolo and Daniel Grasso and M{\'o}nica Nancy Giacomodonato and Mar{\'i}a In{\'e}s Vaccaro},
  journal={Infection and immunity},
  year={2002},
  volume={70 2},
  pages={964-9}
}
Nitric oxide (NO) is a toxic molecule of the immune system which contributes to the control of microbial pathogens. Additional functions of NO in innate and adaptive immunity have recently been described; these functions include the modulation of the cytokine response of lymphocytes and the regulation of immune cell apoptosis. In addition to direct microbicidal actions, NO has immunoregulatory effects relevant to the control of infections. In turn, infected macrophages and macrophage-regulating… CONTINUE READING