Nitric oxide accounts for an increased glycolytic rate in activated astrocytes through a glycogenolysis-independent mechanism.

@article{Almeida2002NitricOA,
  title={Nitric oxide accounts for an increased glycolytic rate in activated astrocytes through a glycogenolysis-independent mechanism.},
  author={Angeles Almeida and Pilar Cidad and Juan P Bola{\~n}os},
  journal={Brain research},
  year={2002},
  volume={945 1},
  pages={131-4}
}
The possible interference of nitric oxide (NO) in glucose metabolism was studied in activated astrocytes. Lipopolysaccharide (LPS) treatment triggered a NO-mediated increase in glucose consumption and lactate production, suggesting an enhanced rate of glycolysis. Active glycogen synthesis was also observed after LPS treatment, but NO synthase inhibition was unable to prevent this effect. These results strongly suggest that endogenously-formed NO stimulates glycolysis through a glycogenolysis… CONTINUE READING

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