Nitric oxide--the endothelium-derived relaxing factor and its role in endothelial functions.

@article{Bauer2010NitricOE,
  title={Nitric oxide--the endothelium-derived relaxing factor and its role in endothelial functions.},
  author={V. Divine Bauer and Ru{\vz}ena Sotn{\'i}kov{\'a}},
  journal={General physiology and biophysics},
  year={2010},
  volume={29 4},
  pages={
          319-40
        }
}
Vascular endothelium plays a key role in the local regulation of vascular tone and vascular architecture by release of vasodilator and vasoconstrictor substances, as well as factors with pro-coagulant, anticoagulant, fibrinolytic, antibacterial properties, growth factors, chemokines, free radicals, etc. Release of endothelium-derived relaxing factors such as nitric oxide (NO), prostaglandins and endothelium-derived hyperpolarizing factor, as well as vasoconstricting factors such as endothelin… CONTINUE READING

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