Nitric oxide: Friend or Foe in Cancer Chemotherapy and Drug Resistance: A Perspective.

@article{Sinha2016NitricOF,
  title={Nitric oxide: Friend or Foe in Cancer Chemotherapy and Drug Resistance: A Perspective.},
  author={B. Sinha},
  journal={Journal of cancer science \& therapy},
  year={2016},
  volume={8},
  pages={
          244-251
        }
}
  • B. Sinha
  • Published 2016
  • Medicine
  • Journal of cancer science & therapy
A successful treatment of cancers in the clinic has been difficult to achieve because of the emergence of drug resistant tumor cells. While various approaches have been tried to overcome multi-drug resistance, it has remained a major road block in achieving complete success in the clinic. Extensive research has identified various mechanisms, including overexpression of P-glycoprotein 170, modifications in activating or detoxification enzymes (phase I and II enzymes), and mutation and/or… Expand
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