Nitric oxide, prostacyclin and cyclic nucleotide formation in externally stented porcine vein grafts.

@article{Jeremy1998NitricOP,
  title={Nitric oxide, prostacyclin and cyclic nucleotide formation in externally stented porcine vein grafts.},
  author={Jamie Yancey Jeremy and Michael Richard Dashwood and Dheeraj Mehta and Mohammed B. Izzat and Nilima Shukla and Gianni Angelini},
  journal={Atherosclerosis},
  year={1998},
  volume={141 2},
  pages={297-305}
}
Non-restrictive, porous, external stents inhibit neointima formation in porcine vein grafts. Since the mechanisms underlying these effects are unknown we investigated the impact of this external stent on factors known to inhibit vascular smooth muscle cell proliferation: prostacyclin (PGI2), nitric oxide (NO), cAMP and cGMP formation in different regions of stented and unstented porcine vein grafts. Paired stented and unstented saphenous vein-carotid artery interposition grafting was carried… CONTINUE READING
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