Nitric oxide, a protective molecule in the cardiovascular system.

  title={Nitric oxide, a protective molecule in the cardiovascular system.},
  author={Jing Lei and Yoram Vodovotz and Edith E. Tzeng and Timothy R Billiar},
  journal={Nitric oxide : biology and chemistry},
Nitric oxide (NO) is an intra- and inter-signaling molecule that regulates vessel dilatation, neuronal transmission, cardiac contraction, immunomodulation, and stem cell differentiation and proliferation. NO plays an important protective role in the cardiovascular system. NO inhibits smooth muscle cells proliferation and migration; enhances proliferation and migration of endothelial cell and inhibits apoptosis; suppresses platelet aggregation; and prevents platelet, leukocyte and monocyte… CONTINUE READING