Nitric Oxide in Retinal and Choroidal Blood Flow Autoregulation in Newborn Pigs: Interactions with Prostaglandins

@article{Hardy1996NitricOI,
  title={Nitric Oxide in Retinal and Choroidal Blood Flow Autoregulation in Newborn Pigs: Interactions with Prostaglandins},
  author={Pierre Hardy and Anne Monique Nuyt and Daniel Abran and Jean St-Louis and D. Ramesh Varma and Sylvain Chemtob},
  journal={Pediatric Research},
  year={1996},
  volume={39},
  pages={487-493}
}
The role of nitric oxide (NO) as well as its interaction with prostaglandins (PG) in setting the limits of autoregulation of retinal blood flow (RBF) and choroidal blood flow (ChBF) were studied in newborn pigs (1-5 d old). Blood flows were measured by the microsphere technique. Low and high ocular perfusion pressures (OPP) were induced by inflating balloon-tipped catheters placed at the aortic root and isthmus, respectively. Animals were treated with the NO synthase inhibitors, NG-nitro-L… CONTINUE READING

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