Nitric Oxide as a Unique Bioactive Signaling Messenger in Physiology and Pathophysiology

  title={Nitric Oxide as a Unique Bioactive Signaling Messenger in
Physiology and Pathophysiology},
  author={N. Tuteja and Mahesh Chandra and R. Tuteja and Mithilesh K. Misra},
  journal={Journal of Biomedicine and Biotechnology},
  pages={227 - 237}
Nitric oxide (NO) is an intra- and extracellular messenger that mediates diverse signaling pathways in target cells and is known to play an important role in many physiological processes including neuronal signaling, immune response, inflammatory response, modulation of ion channels, phagocytic defense mechanism, penile erection, and cardiovascular homeostasis and its decompensation in atherogenesis. Recent studies have also revealed a role for NO as signaling molecule in plant, as it activates… CONTINUE READING


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